The importance of progesterone levels

During ovarian stimulation, administration of GnRH analogues maintains a suppression of endogenous hormone levels. In 5-30% of cases there is a premature increase of progesterone on the day of hCG administration (the last injection of the program).

Several studies have shown that the increase of progesterone above 1 ng/ml is associated with reduced pregnancy rates, while other studies have failed to show such an effect. The mechanism through which pregnancy rates may be affected has not been elucidated yet, but is seems that increased progesterone has a negative impact on the quality of the endometrium.

In view of the contradicting data in the literature, it is important to conduct more prospective randomized controlled trials in a large number of patients, in order to clarify the role of progesterone increase on pregnancy rates.

Eugonia - Assisted Reproduction Unit
Konstantinou Ventiri 7(HILTON), 11528 Athens

  • Email:
  • Τel.: +30 210 723 6333
  • Fax: +30 210 721 3623

Member of:

Google Reviews

Photo gallery

© Copyright 2024 Eugonia - Assisted Reproduction Unit in Greece Developed by NetValue. All rights reserved.