FACULTY OF 1000 MEDICINE
The international scientific organisation FACULTY OF 1000 MEDICINE that reviews and evaluates published clinical studies with significant scientific findings that can change our current clinical practice, evaluated our recently published study titled:
«Flexible GnRH antagonist protocol versus GnRH agonist long protocol in patients with polycystic ovary syndrome treated for IVF: a prospective RCT»
Trifon G Lainas, Ioannis A Sfontouris, Ioannis Z Zorzovilis, George K Petsas, George T Lainas, Efthymia Alexopoulou, Efstratios M Kolibianakis
Human Reproduction, 2010, Vol 25, No.3 pp.683-689.
The two independent reviewers that evaluated our study conclude that: "it is by far the single largest randomized controlled trial performed internationally" and the new antagonists protocol can be proposed as a protocol of choice for women with polycystic ovaries.
The new protocol is more safe and effective than the traditional long protocol, since it presents a statistically reduced chance of severe ovarian hyperstimulation syndrome, a smaller total dose of gonadotrophins and a shorter duration of ovarian stimulation, whilst maintaining the same high pregnancy rates.